P.O. Garkaviy

Heart rate variability peculiarities in patients with arterial hypertension and hypotensive
orthostatic reaction obtaining amlodipin, metoprolol or enalapril maleat treatment

The investigation has been held on 265 patients with arterial hypertension and normotensive
orthostatic reaction or hypotensive orthostatic reaction. 98 patients were obtaining Ca an-
tagonists (amlodipin), 85 ? betablockers (metiprolol), 82 ? ACE inhibitor (enalapril maleat).
Calcium antagonists, beta-blockers and ACE inhibitors have differentl  effects on the heart 
rate variability (HRV) parameters at rest and in tilt tests. In line with the antihyperten-
sive therapy peculiarities found by us, and according to  HRV  changes  ? ACE inhibitors are 
more preferable,  and Ca  antagonists are next to them. Beta-blockers therapy, seems better 
be prescribed in combination with other antihypertensive drugs.