ENALAPRIL TREATMENT EFFECTIVENESS IN ARTERIAL HYPERTENSION ELDERLY PATIENTS
WITH HYPOTENSION ORTHOSTATIC REACTION

P.A. Garkaviy

Therapy effectiveness and orthostatic hypotension (OH) development risk were
studied in 82 elderly arterial  hypertension (AH)  (38 males and 44 females) 
average age — (62,84±5,36) years patients during enalapril treatment. Effec-
tiveness of  enalapril  in AH treatment combined with hydrochlorothiazide if 
required resulted in constant control of SBP and DBP.  On the 2nd week — 1st 
month of enalapril  treatment the frequency of hypotensive orthostatic reac-
tions (HOR) increases from 17 to 24 % on SBP and from 14 to 17 % on DBP, and
then it decreases,  and  up to the 6th month of therapy it is in 21 % on SBP 
and in 16 % on DBP.  This period of AH therapy with enalapril in elderly pa-
tients requires special control for the  probable HOR  development and their 
complications.

Key words: enalapril, arterial blood pressure,  heart rate,  arterial hyper-
tension, orthostatic reactions.